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Title

Azepane quaternary amino acids as effective inducers of 3 10 helix conformations

AuthorsNúñez-Villanueva, D. ; Infantes, L. ; García-López, M. Teresa ; González-Muñiz, Rosario ; Martín-Martínez, Mercedes
Issue Date2012
PublisherAmerican Chemical Society
CitationJournal of Organic Chemistry 77: 9833- 9839 (2012)
AbstractA simple method for the synthesis of an azepane quaternary amino acid in enantiopure form is described. Theoretical, NMR, and X-ray studies indicated that this azepane-derived amino acid is an effective stabilizer of 3 10 helical structures in short peptides.
URIhttp://hdl.handle.net/10261/67015
DOI10.1021/jo301379r
Identifiersdoi: 10.1021/jo301379r
issn: 0022-3263
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