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Organocatalytic activation of imines and related compounds through hydrogen-bond interactions

AuthorsMerino, Pedro ; Delso, J. Ignacio; Tejero, Tomás ; Roca-López, David ; Isasi, Aranzazu; Matute, Rosa
Issue Date2011
PublisherBentham Science Publishers
CitationCurrent Organic Chemistry 15(13): 2184-2209 (2011)
AbstractActivation of imines by hydrogen bonding is a very powerful way of promoting the synthesis of a variety of nitrogencontaining compounds of interest. Such a useful approach typically involves mild reaction conditions, simple experimental operations and metal-free reagents. The present review focuses on the recent development of new organocatalytic methods involving imines and related compounds as substrates in which activation through hydrogen bonding is performed. The different modes of activation are thoroughly illustrated with special emphasis on mechanistic aspects of the reactions and how activation is actually produced. © 2011 Bentham Science Publishers Ltd.
Identifiersdoi: 10.2174/138527211796150660
issn: 1385-2728
Appears in Collections:(ISQCH) Artículos
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