English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/64282
Share/Impact:
Statistics
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:

Title

Absorption of isoflavones in humans: Effects of food matrix and processing

AuthorsPascual-Teresa, Sonia de ; Hallund, J.; Talbot, D.; Schroot, J.; Williams, C.M.; Bugel, S.; Cassidy, A.
Issue Date2006
PublisherElsevier
CitationJournal of Nutritional Biochemistry 17: 257- 264 (2006)
AbstractIf soy isoflavones are to be effective in preventing or treating a range of diseases, they must be bioavailable, and thus understanding factors which may alter their bioavailability needs to be elucidated. However, to date there is little information on whether the pharmacokinetic profile following ingestion of a defined dose is influenced by the food matrix in which the isoflavone is given or by the processing method used. Three different foods (cookies, chocolate bars and juice) were prepared, and their isoflavone contents were determined. We compared the urinary and serum concentrations of daidzein, genistein and equol following the consumption of three different foods, each of which contained 50 mg of isoflavones. After the technological processing of the different test foods, differences in aglycone levels were observed. The plasma levels of the isoflavone precursor daidzein were not altered by food matrix. Urinary daidzein recovery was similar for all three foods ingested with total urinary output of 33-34% of ingested dose. Peak genistein concentrations were attained in serum earlier following consumption of a liquid matrix rather than a solid matrix, although there was a lower total urinary recovery of genistein following ingestion of juice than that of the two other foods. © 2006 Elsevier Inc. All rights reserved.
URIhttp://hdl.handle.net/10261/64282
DOI10.1016/j.jnutbio.2005.04.008
Identifiersdoi: 10.1016/j.jnutbio.2005.04.008
issn: 0955-2863
Appears in Collections:(IF) Artículos
Files in This Item:
File Description SizeFormat 
Absorption of isoflavones in humans.pdf168,07 kBAdobe PDFThumbnail
View/Open
Show full item record
Review this work
 

Related articles:


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.