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Anthocyanins from Eugenia brasiliensis edible fruits as potential therapeutics for COPD treatment

AuthorsFlores, Gema ; Dastmalchi, K.; Paulino, S.; Whalen, K.; Dabo, A. J.; Reynertson, K. A.; Foronjy, R. F.; D'Armiento, J. M.; Kennelly, E. J.
Issue Date2012
CitationFood Chemistry 134: 1256-1262 (2012)
AbstractNine anthocyanins (1-9) from the edible fruits of Eugenia brasiliensis were identified by HPLC-PDA and LC-MS, and seven of these are described for the first time in this Brazilian fruit. Two of the major anthocyanins, delphinidin (8) and cyanidin (9), were studied for their inhibitory activity against chemokine interleukin-8 (IL-8) production before and after cigarette smoke extract (CSE) treatment of cells. In non-treated cells the amount of IL-8 was
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