English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/62620
Share/Impact:
Statistics
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:

Title

HIV-1 tropism evolution after short-term maraviroc monotherapy in HIV-1-infected patients

AuthorsGonzález-Serna, Manuel Alejandro; Romero-Sánchez, M.; Ferrando-Martínez, Sara; Genebat, Miguel; Vidal, Francesc; Muñoz-Fernandez, M. Angeles; Abad Arranz, María; Leal, Manuel; Ruiz-Mateos, Ezequiel
Issue Date2012
PublisherAmerican Society for Microbiology
CitationAntimicrobial Agents and Chemotherapy 56(7): 3981-3983 (2012)
AbstractWe analyzed the evolution of viral tropism after 8 days of maraviroc monotherapy, i.e., we used the maraviroc clinical test (MCT), in 21 patients with and 14 without virological response to the drug (MCT + and MCT - patients, respectively). No increases in CXCR4 inferred viral loads (X4IVLs) were observed in MCT + patients, while X4IVLs increased only in MCT - patients, with X4IVLs of >2 log 10 HIV RNA copies/ml. These results shed light on the evolution of viral tropism under a CCR5 antagonist in vivo. Copyright © 2012, American Society for Microbiology. All Rights Reserved.
URIhttp://hdl.handle.net/10261/62620
DOI10.1128/AAC.00507-12
Identifiersdoi: 10.1128/AAC.00507-12
issn: 0066-4804
Appears in Collections:(IBIS) Artículos
Files in This Item:
File Description SizeFormat 
accesoRestringido.pdf15,38 kBAdobe PDFThumbnail
View/Open
Show full item record
Review this work
 

Related articles:


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.