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Title

Dermoscopic features of skin lesions in patients with mastocytosis

AuthorsVaño-Galvan, Sergio; Álvarez-Twose, Iván; Matito, Almudena; Orfao, Alberto ; Escribano, Luis
Issue Date2011
PublisherAmerican Medical Association
CitationArchives of Dermatology 147(8): 932-940 (2011)
Abstract[Objectives]: To evaluate dermoscopic features in a group of 127 patients with mastocytosis in the skin and to investigate the relationship between different dermoscopic patterns and other clinical and biological characteristics of the disease. [Design]: Clinical and laboratory data were compared among patients with mastocytosis grouped according to the different dermoscopic patterns. [Setting]: Patients were selected from the Instituto de Estudios de Mastocitosis de Castilla La Mancha and the Department of Dermatology of Hospital Universitario Ramón y Cajal from April 1 through September 30, 2009. [Patients]: Overall, 127 consecutive patients (70 females [55.1%] and 57 males [44.9%]; median age, 17 years; range, 0-81 years) with mastocytosis in the skin were included in the study. [Main Outcome Measures]: Evaluation of dermoscopic patterns and investigation of potential predictive factors for more symptomatic forms of the disease according to the need for daily antimediator therapy. [Results]: Four distinct dermoscopic patterns were observed: yellow-orange blot, pigment network, reticular vascular pattern, and (most frequently) light-brown blot. A reticular vascular pattern was identified in all telangiectasia macular eruptiva and some maculopapular mastocytosis. In turn, all patients with mastocytoma displayed the yellow-orange blot pattern. The reticular vascular dermoscopic pattern was associated with the need for daily antimediator therapy; this pattern, together with serum tryptase levels and plaque-type mastocytosis, represented the best combination of independent factors to predict the need for maintained antimediator therapy. [Conclusions]: Dermoscopy is a feasible method for the subclassification of mastocytosis. Of note, a reticular vascular pattern is more frequently associated with the need for antimediator therapy. ©2011 American Medical Association. All rights reserved.
URIhttp://hdl.handle.net/10261/60081
DOI10.1001/archdermatol.2011.190
Identifiersdoi: 10.1001/archdermatol.2011.190
issn: 0003-987X
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