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Título: | Biological activity of secondary metabolites from Bupleurum salicifolium (Umbelliferae) |
Autor: | González-Pérez, José Antonio CSIC ORCID ; Estévez Braun, Ana; Bazzocchi, Isabel L.; Moujir, Laila; Jiménez Díaz, Ignacio Antonio; Ravelo, Ángel G.; González, A. G. | Palabras clave: | Umbelliferae Bupleurum salicifolium Biological activities Polyacetylenes Lignans |
Fecha de publicación: | ene-1995 | Editor: | Springer Nature | Citación: | Experientia 51(1): 35-39 (1995) | Resumen: | Secondary metabolites from Bupleurum salicifolium were tested against viruses, Gram-positive and Gram-negative bacteria, the yeast Candida albicans, the nematodes Globodera pallida and G. rostochiensis, the insect Spodoptera littoralis and the crustacean Artemia salina. These compounds were also tested against tumoral and non-tumoral cell lines. The polyacetylene 8S-heptadeca-2(Z)-9(Z)-diene-4,6-diyne-1,8-diol exhibited toxicity for A. salina and specific antibiotic activity against Gram-positive bacteria. Nine of the lignans and one coumarin showed toxicity for A. salina, and the lignans bursehernin and matairesinol inhibited the hatching of the two nematode species. These are the first lignans that have been reported as affecting phytoparasitic nematodes, and the first natural products known to have an effect on the hatching of G. pallida. Lignans may play a role in the defence mechanisms of potato plants, as allelopathic substances acting against cyst-forming nematodes. | URI: | http://hdl.handle.net/10261/59870 | ISSN: | 0014-4754 |
Aparece en las colecciones: | (IRNAS) Artículos |
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Biological activity of secondary metabolites.pdf | 355,42 kB | Adobe PDF | Visualizar/Abrir |
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