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Ganglioside deriv atives and use thereof as inhibitors of tumour cell division

Other TitlesDerivados de gangliósidos y su uso como inhibidores de la division de células tumorales
AuthorsNieto-Sampedro, Manuel ; Romero-Ramírez, Lorenzo
Issue Date26-Apr-2012
CitationWO2012052596 A1
Abstract[EN] The invention relates to novel inhibitors oftumour cell division. These inhibitors are semi-synthetic derivatives of neurostatin. The invention also relates to a novel method for the synthesis of the inhibitors and neurostatin. In addition, the invention relates to the use of said inhibitors for the production of a drug for the treatment ofbrain tumours.
[ES] La presente invención se refiere a nuevos inhibidores de la división de células tumorales. Dichos inhibidores, son derivados semisintéticos de la neurostatina. Además en la presente invención se describe un nuevo procedimiento de síntesis de los inhibidores y de la neurostatina. Además se describe el uso de estos inhibidores para la fabricación de un medicamento para el tratamiento de tumores cerebrales.
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