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Biomarker discovery by novel sensors based on nanoproteomics approaches

AuthorsDasilva, Noelia; Díez, Paula; Matarraz, Sergio; González González, María; Paradinas, Sara; Orfao, Alberto ; Fuentes, Manuel
Issue Date2012
PublisherMultidisciplinary Digital Publishing Institute
CitationSensors 12(2): 2284-2308 (2012)
AbstractDuring the last years, proteomics has facilitated biomarker discovery by coupling high-throughput techniques with novel nanosensors. In the present review, we focus on the study of label-based and label-free detection systems, as well as nanotechnology approaches, indicating their advantages and applications in biomarker discovery. In addition, several disease biomarkers are shown in order to display the clinical importance of the improvement of sensitivity and selectivity by using nanoproteomics approaches as novel sensors. © 2012 by the authors.
DescriptionThis article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license.-- This article belongs to the Special Issue Biomarkers and Nanosensors: New Approaches for Biology and Medicine.
Publisher version (URL)http://dx.doi.org/10.3390/s120202284
Identifiersdoi: 10.3390/s120202284
issn: 1424-8220
Appears in Collections:(IBMCC) Artículos
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