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Apoptosis in the trabecular meshwork of glaucomatous patients

AuthorsBaleriola, Jimena ; García-Feijóo, Julián; Martínez de la Casa, José M.; Fernández-Cruz, Arturo; De la Rosa, Enrique J. ; Fernández-Durango, Raquel
Issue Date2008
PublisherMolecular Vision
CitationMolecular Vision 14:1513-1516(2008)
AbstractWe established and validated an in toto method to perform TdT-mediated dUTP nick end labeling to study apoptosis in human trabecular meshwork tissue obtained during trabeculectomy in glaucoma patients. In specimens from patients with primary open-angle glaucoma and primary angle-closure glaucoma, we detected a tendency for more apoptotic cells to accumulate in patients with primary open-angle glaucoma. The utility of this method to study apoptosis in the trabecular meshwork is discussed, as well as its application as a tool in biologic samples
Description4 p.-2 fig.-1 tab.
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