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An empirical model for describing the effects of nitrogen sources on nisin production

AuthorsLópez Cabo, Marta ; Murado García, Miguel Anxo ; González Fernández, Pilar ; Vázquez, José Antonio ; Pastoriza, Laura
Issue Date2001
CitationLetters in Applied Microbiology 33(6): 425-429 (2001)
AbstractAims: A study on the effects of tryptone and yeast extract on nisin production by Lactococcus lactis was carried out using a second order rotatable factorial design. Methods and Results: The results show that both ingredients increased nisin production, although a small decrease in nisin levels was noted at high tryptone concentrations. In view of the low vitamin content of tryptone, the amino acids present in both tryptone and yeast extract may be responsible for these observations. Conclusions, Significance and Impact of the Study: The observed response suggests that maintaining tryptone concentrations in the centre of the domain and increasing the concentration of yeast extract would be ideal conditions for nisin production. However, when the economic aspects are considered, it appears that low concentrations of yeast extract and reasonably high concentrations of tryptone are optimal.
Description5 páginas, 2 figuras, 3 tablas
Publisher version (URL)http://dx.doi.org/10.1046/j.1472-765X.2001.01020.x
Appears in Collections:(IIM) Artículos
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