English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/55241
Share/Impact:
Statistics
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:
Title

In vitro bioaccessibility assessment as a prediction tool of nutritional efficiency

AuthorsFernández García, Elisabet ; Carvajal-Lérida, Irene ; Pérez Gálvez, Antonio
KeywordsBioaccessibility
Bioavailability
Food processing
Fortified food
Nutrient content claims
Nutritional efficiency
Issue DateNov-2009
PublisherElsevier
CitationNutrition Research 29(11): 751-760 (2009)
AbstractThe term “bioaccessibility” is a key concept to ascertain nutritional efficiency of food and food formula developed with the aim of improving human health. In this review, working definitions of bioavailability, bioaccessibility, and bioactivity are examined, taking into account the complete sequence of events that take place during the digestive transformation of food into material that can be assimilated by the body, the absorption/assimilation into the cells of the intestinal epithelium, the presystemic metabolism, and, lastly, the development of biologic actions. Comparison among in vivo and in vitro techniques to assess bioaccessibility is accomplished, considering the strengths and limitations of each experimental approach, with a complete description of in vitro procedures applied to determine bioaccessibility of carotenoids. Although a great development has been achieved on the in vitro approaches, these are especially intended for initial screening and should be complemented with in vivo studies, which will remain as the criterion standard for bioaccessibility of nutrients and bioactive compounds at specific target populations. Application of bioaccessibility assessment in foods claiming a health benefit because of their nutrients or bioactive compounds content is described. Measurement of bioaccessibility provides valuable information to select the appropriate dosage and source of food matrices to ensure nutritional efficacy of food products. In addition, in vitro bioactivity measurements to support health benefits of bioactive compounds should be accomplished with estimation of their bioaccessibility, to adequately give nutritional significance to health claims.
Publisher version (URL)http://dx.doi.org//10.1016/j.nutres.2009.09.016
URIhttp://hdl.handle.net/10261/55241
DOI10.1016/j.nutres.2009.09.016
ISSN0271-5317
ReferencesPMID: 19932863
Appears in Collections:(IG) Artículos
Files in This Item:
There are no files associated with this item.
Show full item record
 

Related articles:


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.