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Title

Chelating, antioxidant and antiproliferative activity of Vicia sativa polyphenol extracts

AuthorsMegías, Cristina ; Pastor-Cavada, Elena ; Torres-Fuentes, Cristina ; Girón-Calle, Julio ; Alaíz Barragán, Manuel ; Juan, Rocío; Pastor, Julio E.; Vioque, Javier
KeywordsVicia sativa
Polyphenol extracts
Antioxidant activity
Chelating activity
Antiproliferative activity
Issue Date2-Nov-2009
PublisherSpringer
CitationEuropean Food Research and Technology A 230(2): 353-359 (2009)
AbstractThe metal chelating activity, antioxidant properties, and the effect on cell growth of a polyphenol extract from Vicia sativa have been investigated, and compared to those of soybean. The extracts from V. sativa seeds contained three and five times more polyphenols and flavonoids than soybean, respectively. The soybean polyphenol extracts showed higher copper and iron chelating activity than those from V. sativa, although polyphenols from V. sativa were more effective in preventing β-carotene oxidation and showed higher reducing power and scavenging activity than soybean polyphenols. In addition, V. sativa polyphenols were toxic to THP-1 leukemic cells, as opposed to polyphenols extracted from soybean that did not show any antiproliferative activity at similar concentrations. In conclusion, V. sativa polyphenol extracts show promising antioxidant and antiproliferative activities that may be of interest from a functional point of view and for the revalorization of this ancient crop.
Publisher version (URL)http://dx.doi.org/10.1007/s00217-009-1178-x
URIhttp://hdl.handle.net/10261/55149
DOI10.1007/s00217-009-1178-x
ISSN1438-2377
E-ISSN1438-2385
Appears in Collections:(IG) Artículos
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