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Title

Organocatalytic Enantioselective Henry Reactions

AuthorsÁlvarez-Casao, Yolanda; Marqués-López, Eugenia ; Herrera, Raquel P.
Issue Date2011
PublisherMultidisciplinary Digital Publishing Institute
CitationSymmetry 3(2): 220-245 (2011)
AbstractA large number of interesting organocatalytic enantioselective protocols have been explored and successfully applied in the last decade. Among them, the Henry (nitroaldol) reaction represents a powerful carbon-carbon bond-forming procedure for the preparation of valuable synthetic intermediates, such as enantioenriched nitro alcohols, which can be further transformed in a number of important nitrogen and oxygen-containing compounds. This area of research is still in expansion and a more complex version of this useful process has recently emerged, the domino Michael/Henry protocol, affording highly functionalized cycles with multiple stereogenic centers.
DescriptionThis is an open access article distributed under the Creative Commons Attribution License.
Publisher version (URL)http://dx.doi.org/10.3390/sym3020220
URIhttp://hdl.handle.net/10261/53629
DOI10.3390/sym3020220
Identifiersdoi: 10.3390/sym3020220
issn: 2073-8994
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