English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/52632
Share/Impact:
Statistics
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:
DC FieldValueLanguage
dc.contributor.authorGangoiti, Patricia-
dc.contributor.authorCamacho, Luz-
dc.contributor.authorArana, Lide-
dc.contributor.authorOuro, Alberto-
dc.contributor.authorGranado, María H.-
dc.contributor.authorBrizuela, Leyre-
dc.contributor.authorCasas, Josefina-
dc.contributor.authorFabriàs, Gemma-
dc.contributor.authorAbad, José Luis-
dc.contributor.authorDelgado, Antonio-
dc.contributor.authorGómez-Muñoz, Antonio-
dc.date.accessioned2012-07-02T11:06:17Z-
dc.date.available2012-07-02T11:06:17Z-
dc.date.issued2010-
dc.identifier.citationProgress in Lipid Researches_ES
dc.identifier.issn0163-7827-
dc.identifier.urihttp://hdl.handle.net/10261/52632-
dc.description.abstractSimple bioactive sphingolipids include ceramide, sphingosine and their phosphorylated forms sphingosine 1-phosphate and ceramide 1-phosphate. These molecules are crucial regulators of cell functions. In particular, they play important roles in the regulation of angiogenesis, apoptosis, cell proliferation, differentiation, migration, and inflammation. Decoding the mechanisms by which these cellular functions are regulated requires detailed understanding of the signaling pathways that are implicated in these processes. Most importantly, the development of inhibitors of the enzymes involved in their metabolism may be crucial for establishing new therapeutic strategies for treatment of disease.es_ES
dc.description.sponsorshipCurrent work in A.G.M. laboratory is supported by Grants BFU2009-13314/BMC from “Ministerio de Ciencia e Innovación”, GIC07/63-IT-311-07 from “Departamento de Educación, Universidades e Investigación del Gobierno Vasco, S-PE08UN37 from “Departamento de Industria, Comercio y Turismo del Gobierno Vasco”, and Fundación Ramón Areces (Spain). Work in CID-CSIC is supported by Grants SAF2008-00706 and CTQ2008-01426/BQU from “Ministerio de Ciencia e Innovación”, 2009SGR-01063 (predoctoral fellowship to L.C.) and 2009SGR-1072 from “Generalitat de Catalunya” (Spain).es_ES
dc.language.isoenges_ES
dc.publisherElsevieres_ES
dc.rightsclosedAccesses_ES
dc.subjectApoptosises_ES
dc.subjectCell proliferationes_ES
dc.subjectCeramideses_ES
dc.subjectCeramide kinasees_ES
dc.subjectCeramide-1-phosphatees_ES
dc.subjectCeramidaseses_ES
dc.subjectSphingosine kinasees_ES
dc.subjectInflammationes_ES
dc.subjectMigrationes_ES
dc.subjectSphingolipidses_ES
dc.subjectSphingosine 1-phosphatees_ES
dc.subjectSphingomyelinaseses_ES
dc.titleControl of metabolism and signaling of simple bioactive sphingolipids: Implications in diseasees_ES
dc.typeArtículoes_ES
dc.identifier.doi10.1016/j.plipres.2010.02.004-
dc.description.peerreviewedPeer reviewedes_ES
dc.relation.publisherversionhttp://dx.doi.org/10.1016/j.plipres.2010.02.004es_ES
dc.identifier.e-issn1873-2194-
Appears in Collections:(IQAC) Artículos
Files in This Item:
There are no files associated with this item.
Show simple item record
 

Related articles:


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.