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Camptothecin deriv atives as antitumoural agents

Other TitlesDerivados de camptotecina como agentes antitumorales
AuthorsCorma, Avelino; Díaz Cabañas, María José; Rodríguez Berna, G.; Schwartz, Simó
Issue Date15-Dec-2011
CitationWO2011154574 A1
Abstract[EN] The invention relates to a series of N-substituted 9-(amidomethyl)-1O-hydroxycamptothecin derivatives and Nsubstituted 9-(imidomethyl)-10-hidroxycamptothecin derivatives, that act as antitumoural agents, with a possible application as drugs for curing, stopping or palliating tumours or cancer, such as cancer of the uterus. The invention also relates to the method for the synthesis of said camptothecin derivatives and to the use of said derivatives as antitumoural agents.
[ES] La presente invención se refiere a una serie derivados de derivados de 9- (amidometil) - lO-Hidroxicamptotecinas N-sustituidos y 9-(imidometil) - 10- Hidroxicamptotecinas N-sustituidos, que actúan como agentes antitumorales, con posible aplicación como fánnacos para curar, detener o paliar tumores o cáncer, tales como el cáncer de útero. Del mismo modo, la presente invención, se refiere al procedimiento de síntesis de dichos derivados de la Camptotecina y al uso de los mismos como agentes antitumorales.
Appears in Collections:(ITQ) Patentes
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