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Title

Bifidogenic effect and stimulation of short chain fatty acid production in human faecal slurry cultures by oligosaccharides derived from lactose and lactulose

AuthorsCardelle-Cobas, Alejandra ; Fernández García, María ; Salazar, Nuria ; Martínez Villaluenga, Cristina ; Villamiel, Mar ; Ruas-Madiedo, Patricia ; González de los Reyes-Gavilán, Clara
KeywordsOligosaccharides
Bifidogenic effect
Short chain fatty acids
Lactose
Lactulose
Issue Date18-May-2009
PublisherCambridge University Press
CitationJournal of Dairy Research 76(3): 317-325 (2009)
AbstractBifidogenic effect and stimulation of short chain fatty acid (SCFA) production by fractions of oligosaccharides with a DP≥3 and Gal β(1-6) linkages synthesised from lactose or lactulose by Pectinex Ultra SP-L and Lactozym 3000 L HP G were evaluated in human faecal slurries. Results were compared with those obtained for the commercial oligosaccharide mixture Vivinal®-GOS. Quantitative real-time PCR showed that all galacto-oligosaccharide (GOS) fractions stimulated slightly higher bifidobacteria growth than lactose, lactulose and Vivinal®-GOS. GOS fractions promoted the production of total SCFA and acetic acid in a similar way to Vivinal®-GOS and more than glucose, lactose and lactulose. In conclusion, oligosaccharides derived from lactose and lactulose may represent a suitable alternative to lactulose for the design of new functional food ingredients. © Proprietors of Journal of Dairy Research 2009.
URIhttp://hdl.handle.net/10261/50593
DOI10.1017/S0022029909004063
Identifiersdoi: 10.1017/S0022029909004063
issn: 0022-0299
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