Please use this identifier to cite or link to this item:
http://hdl.handle.net/10261/49730Share/Export:
 SHARE
 CORE
BASE
|
|
| Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
| Title: | Antimicrobial activity of phenolic acids against commensal, probiotic and pathogenic bacteria |
Authors: | Cueva, Carolina CSIC ORCID ; Moreno-Arribas, M. Victoria CSIC ORCID ; Martín-Álvarez, Pedro J. CSIC ORCID; Requena, Teresa CSIC ORCID ; Bartolomé, Begoña CSIC ORCID | Keywords: | Antimicrobial activity Escherichia coli Probiotics Pathogens Phenolic acids |
Issue Date: | Jun-2010 | Publisher: | Elsevier | Citation: | Research in Microbiology 161(5): 372-382 (2010) | Abstract: | Phenolic acids (benzoic, phenylacetic and phenylpropionic acids) are the most abundant phenolic structures found in fecal water. As an approach towards the exploration of their action in the gut, this paper reports the antimicrobial activity of thirteen phenolic acids towards Escherichia coli, Lactobacillus spp., Staphylococcus aureus, Pseudomonas aeruginosa and Candida albicans. The growth of E. coli ATCC 25922 was inhibited by only four of the phenolic acids tested at a concentration of 1000 μg/mL, whereas pathogenic E. coli O157:H7 (CECT 5947) was susceptible to ten of them. The genetically manipulated E. coli lpxC/tolC strain was highly susceptible to phenolic acids. The growth of lactobacilli (Lactobacillus paraplantarum LCH7, Lactobacillus plantarum LCH17, Lactobacillus fermentum LPH1, L. fermentum CECT 5716, Lactobacillus brevis LCH23, and Lactobacillus coryniformis CECT 5711) and pathogens (S. aureus EP167 and C. albicans MY1055) was also inhibited by phenolic acids, but to varying extents. Only P. aeruginosa PAO1 was not susceptible to any of the phenolic compounds tested. Structure–activity relationships of phenolic acids and some of their diet precursors [(+)-catechin and (−)-epicatechin] were established, based on multivariate analysis of microbial activities. The antimicrobial properties of phenolic acids reported in this paper might be relevant in vivo. | Description: | 11 páginas, 4 figuras, 1 tabla.-- et al. | Publisher version (URL): | http://dx.doi.org/10.1016/j.resmic.2010.04.006 | URI: | http://hdl.handle.net/10261/49730 | DOI: | 10.1016/j.resmic.2010.04.006 | ISSN: | 0923-2508 |
| Appears in Collections: | (IF) Artículos (IFI) Artículos |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| accesoRestringido.pdf | 15,38 kB | Adobe PDF |  View/Open |
Review this work
SCOPUSTM
Citations
336
checked on Mar 29, 2023
WEB OF SCIENCETM
Citations
303
checked on Mar 24, 2023
Page view(s)
565
checked on Mar 31, 2023
Download(s)
225
checked on Mar 31, 2023
Google ScholarTM
Check
Altmetric
Altmetric
WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.