English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/49425
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:
DC FieldValueLanguage
dc.contributor.authorPascual-Teresa, Sonia de-
dc.contributor.authorMoreno, Diego A.-
dc.contributor.authorGarcía-Viguera, Cristina-
dc.identifier.citationInternational Journal of molecular science 11 (4): 1679-1703 (2010)es_ES
dc.description25 páginas,4 figuras, 2 tablas.es_ES
dc.description.abstractNowadays it is accepted that natural flavonoids present in fruits and plantderived-foods are relevant, not only for technological reasons and organoleptic properties,but also because of their potential health-promoting effects, as suggested by the availableexperimental and epidemiological evidence. The beneficial biological effects of these foodbioactives may be driven by two of their characteristic properties: their affinity for proteins and their antioxidant activity. Over the last 15 years, numerous publications havedemonstrated that besides their in vitro antioxidant capacity, certain phenolic compounds,such as anthocyanins, catechins, proanthocyanidins, and other non coloured flavonoids,may regulate different signaling pathways involved in cell survival, growth anddifferentiation. In this review we will update the knowledge on the cardiovascular effectsof anthocyanins, catechins and proanthocyanidins, as implied by the in vitro and clinicalstudies on these compounds. We also review the available information on the structure,distribution and bioavailability of flavanols (monomeric catechins and proanthocyanidins)and anthocyanins, data necessary in order to understand their role in reducing risk factorsand preventing cardiovascular health problems through different aspects of theirbioefficacy on vascular parameters (platelet agregation, atherosclerosis, blood pressure,antioxidant status, inflammation-related markers, etc.), myocardial conditions, and wholebodymetabolism (serum biochemistry, lipid profile), highlighting the need for better- designed clinical studies to improve the current knowledge on the potential health benefits of these flavonoids to cardiovascular and metabolic health.es_ES
dc.publisherMultidisciplinary Digital Publishing Institutees_ES
dc.relation.isversionofPublisher’s version-
dc.titleFlavanols and Anthocyanins in Cardiovascular Health: A Review of Current Evidencees_ES
dc.description.peerreviewedPeer reviewedes_ES
Appears in Collections:(ICTAN) Artículos
Files in This Item:
File Description SizeFormat 
Flavanolsde Pascual-Teresa et al2010.pdf175,26 kBAdobe PDFThumbnail
Show simple item record

Related articles:

WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.