English   español  
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/49310
Título

Genomic resources for immunology and disease of salmonid and non-salmonid fish

AutorDios, S. ; Novoa, Beatriz ; Buonocore, Francesco; Scapigliati, Giuseppe; Figueras Huerta, Antonio
Palabras claveImmune response
Resistance
Cloning
ESTs libraries
SSH
Microarrays
Fecha de publicación2008
EditorTaylor & Francis
CitaciónReviews in Fisheries Science 16(S1): 117-130 (2008)
ResumenThe development of aquaculture has increased interest in infectious diseases of fish due to the economic losses in fish farms. Although there are successful vaccines against bacteria, therapeutic treatments for viral diseases have yet to be established. The innate immune system is the first line of defense and therefore an important protection against pathogens in fish. The reason is the relatively inefficiency of the adaptative response in comparison with the unspecific response, given the evolutionary status and poikilothermic nature of these animals. In spite of this, not many innate immune genes have been cloned in fish. However, this number has increased lately owing to the recent advances in genomics and proteomics techniques together with functional studies of gene expression in vivo and in vitro. Many genes and regulatory pathways of biological processes, including defense mechanisms, could be identified and characterized. This knowledge will allow determining the molecular basis of these responses and also be used in the improvement of cultured species via effective fight strategies against pathogens, new vaccine design, and genetic selection of disease-resistant species. In this chapter, we review the application of these techniques to study immune response and disease resistance of non-salmonid and salmonid fish
Descripción13 páginas, 3 tablas
Versión del editorhttp://dx.doi.org/10.1080/10641260701681599
URIhttp://hdl.handle.net/10261/49310
DOI10.1080/10641260701681599
ISSN1064-1262
E-ISSN1547-6553
Aparece en las colecciones: (IIM) Artículos
Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
Genomic resource.doc361,5 kBMicrosoft WordVisualizar/Abrir
Mostrar el registro completo
 

Artículos relacionados:


NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.