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Integrated Bimodal Waveguide Interferometric Biosensor for Label-Free Analysis

AuthorsZinoviev, Kirill; González-Guerrero, Ana Belén CSIC ORCID; Domínguez, Carlos; Lechuga, Laura M. CSIC ORCID
KeywordsBimodal waveguide
Evanescent wave detection
Integrated optics
Optical biosensors
Issue DateJul-2011
PublisherInstitute of Electrical and Electronics Engineers
CitationJournal of Lightwave Technology 29(13): 1926-1930 (2011)
AbstractThe performance of an interferometric device based on integrated Bimodal Waveguides (BiMW) for sensing is demonstrated. The sensors are fabricated using standard silicon technology and can achieve a detection limit of 2.5·10- 7 RIU for homogeneous sensing, rendering in a very high sensitive device. The applicability of the bimodal waveguide interferometer as label-free biosensor has been demonstrated by the real-time monitoring of the biomolecular interaction of BSA and antiBSA. Due to their simplicity, the interferometric devices could be further integrated in complete lab-on-a-chip platforms for point-of-care diagnostics showing them as a powerful instrument for biochemical analysis.
Description5 páginas, 8 figuras, 1 tabla.-- El pdf del artículo es la versión post-print.
Publisher version (URL)http://dx.doi.org/10.1109/JLT.2011.2150734
Appears in Collections:(CIN2) Artículos
(IMB-CNM) Artículos
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