English   español  
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/4822
Compartir / Impacto:
Estadísticas
Add this article to your Mendeley library MendeleyBASE
Ver citas en Google académico
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar otros formatos: Exportar EndNote (RIS)Exportar EndNote (RIS)Exportar EndNote (RIS)
Título : A message emerging from development: the repression of mitochondrial β-F1-ATPase expression in cancer
Autor : Cuezva, José M.; Sánchez-Aragó, María; Sala, Sandra; Blanco-Rivero, Amaya; Ortega, Álvaro D.
Palabras clave : Mitochondria
H+-ATP synthase
Oxidative phosphorylation
Glycolysis
Cancer
Fecha de publicación : 28-ago-2007
Editor: Springer
Citación : Journal of Bioenergetics & Biomembranes Vol.39 (3) 259-265 (2007)
Resumen: Mitochondrial research has experienced a considerable boost during the last decade because organelle malfunctioning is in the genesis and/or progression of a vast array of human pathologies including cancer. The renaissance of mitochondria in the cancer field has been promoted by two main facts: (1) the molecular and functional integration of mitochondrial bioenergetics with the execution of cell death and (2) the implementation of 18FDG-PET for imaging and staging of tumors in clinical practice. The latter, represents the bed-side translational development of the metabolic hallmark that describes the bioenergetic phenotype of most cancer cells as originally predicted at the beginning of previous century by Otto Warburg. In this minireview we will briefly summarize how the study of energy metabolism during liver development forced our encounter with Warburg’s postulates and prompted us to study the mechanisms that regulate the biogenesis of mitochondria in the cancer cell
Descripción : The original publication is available at www.springerlink.com http://dx.doi.org/10.1007/s10863-007-9087-9
URI : http://hdl.handle.net/10261/4822
ISSN: 0145-479X (Print)
1573-6881 (Online)
Aparece en las colecciones: (CBM) Artículos
Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
Cuezva_JBB_259.pdf223,52 kBAdobe PDFVista previa
Visualizar/Abrir
Mostrar el registro completo
 


NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.