English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/48218
Share/Impact:
Statistics
logo share SHARE   Add this article to your Mendeley library MendeleyBASE
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:

DC FieldValueLanguage
dc.contributor.authorRoch, Fernando-
dc.contributor.authorBaonza, Antonio-
dc.contributor.authorMartín-Blanco, Enrique-
dc.contributor.authorGarcía-Bellido, Antonio-
dc.date.accessioned2012-04-12T18:17:10Z-
dc.date.available2012-04-12T18:17:10Z-
dc.date.issued1998-
dc.identifier.citationDevelopment 125, 1823-1832 (1998)es_ES
dc.identifier.issn1011-6370-
dc.identifier.urihttp://hdl.handle.net/10261/48218-
dc.description.abstractIn this work, we analyse the blistered function in wing vein development by studying genetic mosaics of mutant cells, genetic interactions with other genes affecting vein development and blistered expression in several mutant backgrounds. blistered encodes for a nuclear protein homologous to the mammalian Serum Response Factor and is expressed in presumptive intervein cells of third larval instar and pupal wing discs. Clones of blistered mutant cells proliferate normally but tend to grow along veins and always differentiate as vein tissue. These observations indicate that vein-determined wing cells show a particular behaviour that is responsible for their allocation to vein regions. We observe strong genetic interactions between blistered, veinlet and genes of the Ras signaling cascade. During disc proliferation, blistered expression is under the control of the Ras signal transduction pathway, but its expression is independent of veinlet. During the pupal period, blistered and veinlet expression become interdependent and mutually exclusive. These results link the activity of the Ras pathway to the process of early determination of intervein cells, by the transcriptional control of the blistered nuclear factor.es_ES
dc.language.isoenges_ES
dc.publisherCompany of Biologistses_ES
dc.rightsclosedAccesses_ES
dc.subjectDrosophilaes_ES
dc.subjectWinges_ES
dc.subjectBlisteredes_ES
dc.subjectMutant Cellses_ES
dc.titleGenetic interactions and cell behaviour in blistered mutants during proliferation and differentiation of the Drosophila winges_ES
dc.typeartículoes_ES
dc.description.peerreviewedPeer reviewedes_ES
dc.relation.publisherversionhttp://dev.biologists.org/cgi/pmidlookup?view=long&pmid=9550715es_ES
Appears in Collections:(CBM) Artículos
Files in This Item:
File Description SizeFormat 
Embargo.pdf21,67 kBAdobe PDFThumbnail
View/Open
Show simple item record
 


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.