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Título: | Cell cycling and patterned cell proliferation in the wing primordium of Drosophila. |
Autor: | Milán, Marco; Campuzano, Sonsoles CSIC ORCID; García-Bellido, Antonio CSIC | Palabras clave: | Drosophila Genes Wing Imaginal |
Fecha de publicación: | 1996 | Editor: | National Academy of Sciences (U.S.) | Citación: | Proceedings of the National Academy of Sciences 93 (2): 640–645. (1996) | Resumen: | The pattern of cell proliferation in the Drosophila imaginal wing primordium is spatially and temporally heterogeneous. Direct visualization of cells in S, G2, and mitosis phases of the cell cycle reveals several features invariant throughout development. The fraction of cells in the disc in the different cell cycle stages is constant, the majority remaining in G1. Cells in the different phases of the cell cycle mainly appear in small synchronic clusters that are nonclonally derived but result from changing local cell-cell interactions. Cluster synchronization occurs before S and in the G2/M phases. Rates of cell division are neither constant nor clonal features. Cell cycle progression is linear rather than concentric. Clusters appear throughout the disc but with symmetries related to presumptive wing patterns, compartment boundaries, and vein clonal restrictions. | Versión del editor: | http://dx.doi.org/10.1073/pnas.93.2.640 | URI: | http://hdl.handle.net/10261/48127 | DOI: | 10.1073/pnas.93.2.640 | E-ISSN: | 1091-6490 |
Aparece en las colecciones: | (CBM) Artículos |
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