English   español  
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/4779
Compartir / Impacto:
Estadísticas
Add this article to your Mendeley library MendeleyBASE
Citado 394 veces en Web of Knowledge®  |  Pub MebCentral Ver citas en PubMed Central  |  Ver citas en Google académico
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar otros formatos: Exportar EndNote (RIS)Exportar EndNote (RIS)Exportar EndNote (RIS)
Título : The penicillin-binding proteins: structure and role in peptidoglycan biosynthesis
Autor : Sauvage, Eric; Kerff, Frédéric; Terrak, Mohammed; Ayala, Juan Alfonso
Palabras clave : Penicillin binding
Transpeptidase
Transglycosylase
Peptidoglycan synthesis
3D structure
Fecha de publicación : feb-2008
Editor: Blackwell Publishing
Citación : FEMS Microbiology Reviews Vol.32 Issue 2 Page 234-258, 2008
Erratum printed in: vol.32 Issue 3 Page 556
Resumen: Penicillin-binding proteins (PBPs) have been scrutinized for over 40 years. Recent structural information on PBPs together with the ongoing long-term biochemical experimental investigations, and results from more recent techniques such as protein localization by green fluorescent protein-fusion immunofluorescence or double-hybrid assay, have brought our understanding of the last stages of the peptidoglycan biosynthesis to an outstanding level that allows a broad outlook on the properties of these enzymes. Details are emerging regarding the interaction between the peptidoglycan-synthesizing PBPs and the peptidoglycan, their mesh net-like product that surrounds and protects bacteria. This review focuses on the detailed structure of PBPs and their implication in peptidoglycan synthesis, maturation and recycling. An overview of the content in PBPs of some bacteria is provided with an emphasis on comparing the biochemical properties of homologous PBPs (orthologues) belonging to different bacteria
Versión del editor: http://dx.doi.org/10.1111/j.1574-6976.2008.00105.x
URI : http://hdl.handle.net/10261/4779
DOI: 10.1111/j.1574-6976.2008.00105.x
ISSN: 0168-6445
Aparece en las colecciones: (CBM) Artículos
Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
Ayala_FemsMicroRev_234.pdf5,28 MBAdobe PDFVista previa
Visualizar/Abrir
Mostrar el registro completo
 



NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.