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Nanomechanical coupling enables detection and imaging of 5 nm superparamagnetic particles in liquid

AuthorsDietz, Christian ; Herruzo, Elena T. ; Lozano, José R.; García García, Ricardo
KeywordsSoft matter, liquids and polymers
Nanoscale science and low-D systems
Issue Date17-Feb-2011
PublisherInstitute of Physics Publishing
CitationNanotechnology 22(12): 125708 (2012)
AbstractWe demonstrate that a force microscope operated in a bimodal mode enables the imaging and detection of superparamagnetic particles down to 5 nm. The bimodal method exploits the nanomechanical coupling of the excited modes to enhance the sensitivity of the higher mode to detect changes in material properties. The coupling requires the presence of nonlinear forces. Remarkably, bimodal operation enables us to identify changes of slowly varying forces (quasi-linear) in the presence of a stronger nonlinear force. Thus, unambiguous identification of single apoferritin (non-magnetic) and ferritin (magnetic) molecules in air and liquid is accomplished.
Publisher version (URL)http://dx.doi.org/10.1088/0957-4484/22/12/125708
Appears in Collections:(IMN-CNM) Artículos
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