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Título

A model for somatic pairing derived from somatic crossing over with third chromosome rearrangements in Drosophila melanogaster

AutorMerriam, John R.; García-Bellido, Antonio
Palabras claveX-ray
Drosophila melanogaster
Heterozygotes
Cells
Fecha de publicación1972
EditorSpringer
CitaciónMolecular and General Genetics, 115 (4): 302-313 (1972)
ResumenX-ray induced crossing-over between the left arms of third chromosome pairs heterozygous for rearrangements was used to measure the somatic pairing of these arms. mwh spots were scored in the wing blades. A significantly reduced number of crossover spots is found in flies heterozygous for inversions or translocations located in the 3L arm. This decrease from control frequencies was experimentally demonstrated to be due to inviability of some crossover spots which are aneuploid as a result of crossing-over within the inverted sequence or between the translocation piece and its centromere. By the same token, some euploid crossover spots are produced by crossing-over outside of the inverted region or between the translocation breakpoint and the mwh locus. Thus, these results are evidence that the euchromatic non-centric portions of the 3L arms are somatically paired in the presence of rearrangements. A model of somatic pairing in which chromosomes are normally found in a ldquohair pinrdquo configuration is proposed to account for these results and for some previous results with X-chromosomes which indicated that inversion heterozygotes did not pair somatically.
Versión del editorhttp://dx.doi.org/10.1007/BF00333169
URIhttp://hdl.handle.net/10261/47365
DOI10.1007/BF00333169
ISSN1617-4615
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