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Title

Modified siRNAs for the study of the PAZ domain

AuthorsSomoza, Álvaro; Terrazas, Montserrat; Eritja Casadellà, Ramón
Issue Date2010
PublisherRoyal Society of Chemistry (Great Britain)
CitationChemical Communications
AbstractChemical modifications aimed at stabilizing the interaction between the 3′-end of siRNAs and the PAZ domain of RISC have been tested for their effect on RNAi activity. Such modifications contribute positively to the stability of siRNAs in human serum.
Publisher version (URL)http://dx.doi.org/10.1039/C003221B
URIhttp://hdl.handle.net/10261/47223
DOI10.1039/C003221B
ISSN1359-7345
E-ISSN1364-548X
Appears in Collections:(IQAC) Artículos
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