Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/44402
COMPARTIR / EXPORTAR:
logo share SHARE logo core CORE BASE
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE

Invitar a revisión por pares abierta
Campo DC Valor Lengua/Idioma
dc.contributor.authorJagerovic, Nadine-
dc.contributor.authorHernández-Folgado, Laura-
dc.contributor.authorAlkorta, Ibon-
dc.contributor.authorGoya, Pilar-
dc.contributor.authorSerrano, Antonia-
dc.contributor.authorRodríguez de Fonseca, Fernando-
dc.contributor.authorDannert, M. Teresa-
dc.contributor.authorAlsasua, Ángela-
dc.contributor.authorSuardiaz, Margarita-
dc.contributor.authorPascual, David-
dc.contributor.authorMartín, M. Isabel-
dc.date.accessioned2012-01-18T09:48:11Z-
dc.date.available2012-01-18T09:48:11Z-
dc.date.issued2004-05-20-
dc.identifier.citationJournal of Medicinal Chemistry 47 (11) : 2939–2942 (2004)es_ES
dc.identifier.issn0022-2623-
dc.identifier.urihttp://hdl.handle.net/10261/44402-
dc.description.abstractA new series of 1,2,4-triazoles have been prepared and the evaluation of their cannabinoid properties have been carried out. Compound 8 showed cannabinoid silent antagonist activity in mouse vas deferens and guinea pig ileum preparations and in vivo assays (cannabinoid tetrad) in mouse. It did not have intrinsic activity in these bioassays, and therefore, it did not behave as a partial agonist or an inverse agonistes_ES
dc.description.sponsorshipThis work was supported by Spanish Grant SAF 00-0114-C02. L.H.-F. is recipient of the I3P Fellowship from the C.S.I.C. Laboratorios Dr. Esteve, S.A. is gratefully acknowledged. L.H.-F. thanks the Spanish Society of Therapeutic Chemistry (SEQT) for the Ramon Madroñero Young Researcher Award.es_ES
dc.language.isoenges_ES
dc.publisherAmerican Chemical Societyes_ES
dc.rightsclosedAccesses_ES
dc.subjectCannabinoid antagonistes_ES
dc.titleDiscovery of 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-hexyl-1H-1,2,4-triazole, a novel in vivo cannabinoid antagonist containing a 1,2,4-triazole motifes_ES
dc.typeartículoes_ES
dc.identifier.doi10.1021/jm031099y-
dc.description.peerreviewedPeer reviewedes_ES
dc.relation.publisherversionhttp://dx.doi.org/10.1021/jm031099yes_ES
dc.type.coarhttp://purl.org/coar/resource_type/c_6501es_ES
item.openairetypeartículo-
item.cerifentitytypePublications-
item.languageiso639-1en-
item.grantfulltextnone-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextNo Fulltext-
Aparece en las colecciones: (IQM) Artículos
Show simple item record

CORE Recommender

SCOPUSTM   
Citations

76
checked on 25-mar-2024

WEB OF SCIENCETM
Citations

73
checked on 29-feb-2024

Page view(s)

339
checked on 29-mar-2024

Google ScholarTM

Check

Altmetric

Altmetric


NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.