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Título

Optical sensors based on evanescent field sensing Part II. Integrated optical sensors

AutorLechuga, Laura M.
Palabras claveOptical waveguides
Evanescent wave
Integrated optics
Biospecific molecular interaction
Fecha de publicación2000
EditorSociedad Española de Química Analítica
CitaciónQuímica Analítica 19(Supl. 1): 61-67 (2000)
ResumenEvanescent wave optical sensors are analytical devices that measure the interaction between complementary molecules in real time, without the need of labels. The selective receptor molecules are immobilised on the sensor surface and a solution with the complementary analyte is flowing over the surface. Binding is measured by changes in the refractive index due to the molecular interaction near the sensor surface within ihe evanescent region. In this way, evanescent wave sensors are selective and sensitive devices for the detection of very low levels of chemicals and biological substances and for the measurement of molecular interactions in-situ and in real time. Several of these sensors have been reported in the literature in the last decade: the grating coupler, the vibrating mirror, the difference refractometer, the Mach-Zehnder Interferometer, among the most important ones. Actually, there are two commercial devices on the market. This review describes the physical principie of function, the technology, the most important applications and the future trends of these íntegrated optical sensors.
Descripción7 páginas, 7 figuras.
Versión del editorhttp://www.seqa.es/site/index.php?option=com_content&task=view&id=113&Itemid=112
URIhttp://hdl.handle.net/10261/43127
ISSN0212-0569
Aparece en las colecciones: (IMN-CNM) Artículos
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