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dc.contributor.authorCobreros, Laura-
dc.contributor.authorFernández-Miñán, Ana-
dc.contributor.authorFernández-Espartero, Cecilia H.-
dc.contributor.authorLópez-Schier, Hernán-
dc.contributor.authorGonzález-Reyes, Acaimo-
dc.contributor.authorMartín-Bermudo, María D.-
dc.date.accessioned2011-10-20T13:05:11Z-
dc.date.available2011-10-20T13:05:11Z-
dc.date.issued2010-11-12-
dc.identifier.citationEMBO Reports 11(12): 943-949 (2010)es_ES
dc.identifier.issn1469-221X-
dc.identifier.otherPMID: 21102643-
dc.identifier.otherPMC2999858-
dc.identifier.urihttp://hdl.handle.net/10261/41505-
dc.description7 páginas, 5 figuras.es_ES
dc.description.abstractStationary-to-migratory transitions of epithelial cells have a key role in development and tumour progression. Border cell migration is a powerful system in which to investigate this transition in living organisms. Here, we identify the Ste20-like kinase misshapen (msn) as a novel regulator of border-cell migration in Drosophila. Expression of msn in border cells is independent of the transcription factor slow border cells and of inputs from all pathways that are known to control border-cell migration. The msn gene functions to modulate the levels and/or distribution of Drosophila E-cadherin to promote the invasive migratory behaviour of border cells.es_ES
dc.description.sponsorshipFunding from the Spanish Ministerio de Ciencia e Innovación (MICINN), the EMBO Young Investigator Programme and the Junta de Andalucía is acknowledged.es_ES
dc.language.isoenges_ES
dc.publisherJohn Wiley & Sonses_ES
dc.rightsclosedAccesses_ES
dc.subjectSte20 kinaseses_ES
dc.subjectCell migrationes_ES
dc.subjectSignallinges_ES
dc.subjectDE-cadherines_ES
dc.subjectDrosophilaes_ES
dc.subjectOvaryes_ES
dc.subjectEpithelial cellses_ES
dc.subjectJNK mitogen-activated protein kinaseses_ES
dc.titleThe Ste20 kinase misshapen is essential for the invasive behaviour of ovarian epithelial cells in Drosophilaes_ES
dc.typeartículoes_ES
dc.identifier.doi10.1038/embor.2010.156-
dc.description.peerreviewedPeer reviewedes_ES
dc.relation.publisherversionhttp://dx.doi.org/10.1038/embor.2010.156es_ES
dc.identifier.e-issn1469-3178-
dc.contributor.funderMinisterio de Ciencia e Innovación (España)-
dc.contributor.funderJunta de Andalucía-
dc.relation.csic-
dc.identifier.funderhttp://dx.doi.org/10.13039/501100004837es_ES
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