English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/40135
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE
Exportar a otros formatos:


An evaluation of the sexual differences in the accumulation of organochlorine compounds in children at birth and at the age of four years

AuthorsGrimalt, Joan O. ; Carrizo, Daniel; Garcí, Mercè; Font-Ribera, Laia; Ribas-Fitó, Núria; Torrent, Matties; Sunyer, Jordi
KeywordsOrganochlorine compounds
persistent organic pollutants
pollutants in cord serum
background concentrations of organochlorine compounds in children sera
Issue Date1-Feb-2010
CitationEnvironmental Research 110 (3): 244-250 (2010)
AbstractThis study of the body burden and serum concentrations, of organochlorine compounds (OCs), represents a general population in a cohort from Menorca Island (birth 1997-1998) of children at birth and at four years of age; the study has shown that the concentrations of hexachlorobenzene (HCB), 4,4’-DDE, 4,4’-DDT, polychlorobiphenyl (PCB) congeners #153, #138 and #180 and total PCBs in sera collected at four years exhibit much higher values in breastfed children than in those fed with formula, e.g. HCB 0.48 vs 0.21 ng/ml, β-HCH 0.32 vs 0.24 ng/ml, total DDTs 2.2 vs 0.57 ng/ml, total PCBs 1.4 vs 0.52 ng/ml, respectively. Comparison of gender differences in four years old children shows higher concentrations of all examined OCs in females than in males with the exception of HCB and PeCB in breastfed children which are higher in males than in females, e.g. β-HCH 0.34 vs 0.28 ng/ml, total DDTs 2.6 vs 1.7 ng/ml, total PCBs 1.6 vs 1.0 ng/ml, respectively, for breastfed children and e.g. β-HCH 0.23 vs 0.19 ng/ml, total DDTs 0.59 vs 0.48 ng/ml, total PCBs 0.58 vs 0.45 ng/ml, respectively, for formula fed children. Gender comparison of the body burden between children fed with breast milk or formula also shows higher concentrations in females than males, e.g. β-HCH 0.47 vs 0.35 µg, total DDTs 3.0 vs 1.8 µg, total PCBs 1.9 vs 1.2 µg, respectively, for breastfed children, and β-HCH 0.39 vs 0.17 µg, total DDTs 0.48 vs 0.27 µg, total PCBs 0.66 vs 0.55 µg, respectively, for formula fed children. The results may suggest a higher capacity in female children for the retention of OC incorporated through breast feeding. However, these results should be taken with caution because the differences of the gender averages have low statistically significance when evaluated with the Student test.
Description7 páginas, 2 figuras, 5 tablas.
Publisher version (URL)http://dx.doi.org/10.1016/j.envres.2010.01.005
Appears in Collections:(IDAEA) Artículos
Files in This Item:
File Description SizeFormat 
Organochroline_manuscript_Grimalt.pdfArtículo principal145,57 kBAdobe PDFThumbnail
Figure 1 new.pdfFigura 119,88 kBAdobe PDFThumbnail
Figure 2 new.pdfFigura 223,82 kBAdobe PDFThumbnail
Table 1 new.docTabla 137 kBMicrosoft WordView/Open
Table 2 new.docTabla 246 kBMicrosoft WordView/Open
Table 3 new.docTabla 362 kBMicrosoft WordView/Open
Table 4 new.docTabla 463 kBMicrosoft WordView/Open
Table 5 new.docTabla 562,5 kBMicrosoft WordView/Open
Show full item record
Review this work

Related articles:

WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.