Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/38269
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Título: | Iron(III)-Catalyzed Consecutive Aza-Cope−Mannich Cyclization: Synthesis of trans-3,5-Dialkyl Pyrrolidines and 3,5-Dialkyl-2,5-dihydro-1H-pyrroles |
Autor: | Carballo, Rubén M.; Ramírez, Miguel A.; Padrón, Juan I. CSIC ORCID | Fecha de publicación: | 2010 | Editor: | American Chemical Society | Citación: | Organic Letters 12(22): 5334-5337 (2010) | Resumen: | An efficient alkene aza-Cope−Mannich cyclization between 2-hydroxy homoallyl tosylamine and aldehydes in the presence of iron(III) salts to obtain 3-alkyl-1-tosyl pyrrolidines in good yields is described. The process is based on the consecutive generation of a γ-unsaturated iminium ion, 2-azonia-[3,3]-sigmatropic rearrangement, and further intramolecular Mannich reaction. Iron(III) salts are also shown to be excellent catalysts for the new aza-Cope−Mannich cyclization using 2-hydroxy homopropargyl tosylamine. | Descripción: | 4 páginas. 1 figura, 4 esquemas, 3 tablas. | Versión del editor: | http://dx.doi.org/10.1021/ol102372c | URI: | http://hdl.handle.net/10261/38269 | DOI: | 10.1021/ol102372c | ISSN: | 1523-7060 |
Aparece en las colecciones: | (IPNA) Artículos |
Mostrar el registro completo
CORE Recommender
SCOPUSTM
Citations
33
checked on 17-abr-2024
WEB OF SCIENCETM
Citations
32
checked on 23-feb-2024
Page view(s)
328
checked on 24-abr-2024
Google ScholarTM
Check
Altmetric
Altmetric
NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.