English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/37657
Share/Impact:
Statistics
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:

Title

Generalized Anomeric Effect in gem-Diamines: Stereoselective Synthesis of α-N-Linked Disaccharide Mimics

AuthorsSánchez-Fernández, Elena M. ; Rísquez-Cuadro, Rocio; Aguilar Moncayo, Matilde ; García Moreno, María Isabel; Ortiz-Mellet, Carmen; García-Fernández, José Manuel
KeywordsDiamines
Enzyme inhibitors
Glucosamine
Isomaltose
Maltose
Molecular mimcry
Stereoisomerism
Glycopyranosylamine
Disaccharide
Issue Date16-Jul-2009
PublisherAmerican Chemical Society
CitationOrganic Letters 11(15): 3306-3309 (2009)
AbstractThe orbital (negative hyperconjugation) contribution to the generalized anomeric effect is highly increased in bicyclic gem-diamines with a pseudoamide-type endocyclic nitrogen atom, which has been exploited for the stereoselective synthesis of configurationally stable alpha-N-linked azadisaccharide heteroanalogues of the natural disaccharides maltose and isomaltose as aglycon-sensitive inhibitors of isomaltase.
Description4 páginas, 2 figuras, 3 esquemas.
Publisher version (URL)http://dx.doi.org/10.1021/ol901125n
URIhttp://hdl.handle.net/10261/37657
DOI10.1021/ol901125n
ISSN1523-7060
Appears in Collections:(IIQ) Artículos
Files in This Item:
There are no files associated with this item.
Show full item record
Review this work
 

Related articles:


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.