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| Title: | Tailoring β-Cyclodextrin for DNA Complexation and Delivery by Homogeneous Functionalization at the Secondary Face |
| Authors: | Ortega-Caballero, Fernando; Ortiz-Mellet, Carmen; Gourriérec, Loïc le; Guilloteau, Nicolas; Giorgo, Christophe di; Vierling, Pierre; Defaye, Jacques; García-Fernández, José Manuel |
| Keywords: | Animals Cell line DNA Mice Transfection Beta-Cyclodextrins Betadex |
| Issue Date: | 21-Oct-2008 |
| Publisher: | American Chemical Society |
| Citation: | Organic Letters 10(22): 5143-5146 (2008) |
| Abstract: | An efficient general strategy for the incorporation of functional elements onto the secondary hydroxyl rim of beta-cyclodextrin has been developed and applied to the synthesis of a novel series of C7-symmetric homogeneous macromolecular polycations with improved DNA complexing and delivery properties. |
| Description: | 4 páginas, 2 figuras, 3 esquemas |
| Publisher version (URL): | http://dx.doi.org/10.1021/ol802081z |
| URI: | http://hdl.handle.net/10261/37636 |
| DOI: | 10.1021/ol802081z |
| ISSN: | 1523-7060 |
| Appears in Collections: | (IIQ) Artículos |
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