Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/37481
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.contributor.author | Canales, Ángeles | - |
dc.contributor.author | Angulo, Jesús | - |
dc.contributor.author | Ojeda, Rafael | - |
dc.contributor.author | Bruix, M. | - |
dc.contributor.author | Fayos, Rosa | - |
dc.contributor.author | Lozano, R.M. | - |
dc.contributor.author | Giménez-Gallego, Guillermo | - |
dc.contributor.author | Martín-Lomas, Manuel | - |
dc.contributor.author | Nieto, Pedro M. | - |
dc.contributor.author | Jiménez-Barbero, Jesús | - |
dc.date.accessioned | 2011-07-04T12:50:35Z | - |
dc.date.available | 2011-07-04T12:50:35Z | - |
dc.date.issued | 2005-04-02 | - |
dc.identifier.citation | Journal of the American Chemical Society 127(16): 5778-5779 (2005) | es_ES |
dc.identifier.issn | 0002-7863 | - |
dc.identifier.uri | http://hdl.handle.net/10261/37481 | - |
dc.description | 2 páginas, 1 figura, 1 tabla, esquemas. | es_ES |
dc.description.abstract | The first direct NMR determination of the conformation of a conformationally flexible heparin-like hexasaccharide bound to a key receptor, FGF-1, is described. The determination has been based on the use of a 13C-labeled protein and a regular 12C sugar. FGF-1 recognizes several conformations of the iduronic moieties of the hexasaccharide. Therefore, this case is different than that described for the controversial recognition of heparin-like saccharides by AT-III, which seems to recognize just one conformation of the iduronic acid residues. | es_ES |
dc.description.sponsorship | Financial support by DGICYT (BQU2003-03550, BQU2002-03734, BIO2002-00305) is acknowledged. We also thank Fundación Ramón Areces and Francisco Cobos for fellowships to J.A. and R.O. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | American Chemical Society | es_ES |
dc.rights | closedAccess | es_ES |
dc.subject | NMR | es_ES |
dc.subject | FGF-1 | es_ES |
dc.subject | Sugar | es_ES |
dc.subject | Hexasaccharide | es_ES |
dc.subject | Iduronic acid | es_ES |
dc.title | Conformational Flexibility of a Synthetic Glycosylaminoglycan Bound to a Fibroblast Growth Factor. FGF-1 Recognizes Both the 1C4 and 2SO Conformations of a Bioactive Heparin-like Hexasaccharide | es_ES |
dc.type | artículo | es_ES |
dc.identifier.doi | 10.1021/ja043363y | - |
dc.description.peerreviewed | Peer reviewed | es_ES |
dc.relation.publisherversion | http://dx.doi.org/10.1021/ja043363y | es_ES |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
item.languageiso639-1 | en | - |
item.fulltext | No Fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | none | - |
item.openairetype | artículo | - |
Aparece en las colecciones: | (IIQ) Artículos (ICMM) Artículos (IQF) Artículos |
CORE Recommender
SCOPUSTM
Citations
67
checked on 29-mar-2024
WEB OF SCIENCETM
Citations
69
checked on 25-feb-2024
Page view(s)
438
checked on 23-abr-2024
Google ScholarTM
Check
Altmetric
Altmetric
NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.