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Title

Rational design of cationic cyclooligosaccharides as efficient gene delivery systems

AuthorsDíaz Moscoso, Alejandro ; Balbuena Olivia, Patricia ; Gómez García, Marta ; Ortiz-Mellet, Carmen; Benito, Juan M. ; Gourriérec, Loïc le; Giorgo, Christophe di; Vierling, Pierre; Mazzaglia, Antonio; Micali, Norberto; Defaye, Jacques; García-Fernández, José Manuel
KeywordsCyclodextrin
CDplexes
Nanoparticles
Polyplexes
β-cyclodextrin
Cationic cyclooligosaccharides
Issue Date25-Feb-2008
PublisherRoyal Society of Chemistry (UK)
CitationChemical Communications (17): 2001-2003 (2008)
AbstractSelf-assembled cyclodextrin (CD)–DNA nanoparticles (CDplexes) exhibiting transfection efficiencies significantly higher than PEI-based polyplexes have been prepared from homogeneous seven-fold symmetric polyaminothiourea amphiphiles constructed on a β-cyclodextrin scaffold.
Description3 páginas, 2 figuras, 1 esquema
Publisher version (URL)http://dx.doi.org/10.1039/B718672J
URIhttp://hdl.handle.net/10261/36328
DOI10.1039/B718672J
ISSN1359-7345
Appears in Collections:(IIQ) Artículos
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