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Conformational studies of 3'-spironucleosides (TSAO-T and analogues) by NMR spectroscopy

AuthorsÁlvarez, Rosa; Jimeno, M. Luisa ; Tomas-Gil, Francisco J.; Pérez Pérez, María Jesús; Camarasa Rius, María José
Issue Date1997
PublisherTaylor & Francis
CitationNucleosides, Nucleotides and Nucleic Acids 16(7 & 9) : 1399 - 1402 (1997)
AbstractThe conformational properties in solution of the prototype compound TSAO-T (1) and its two analogues 2 and 3 have been determined by H and C NMR techniques. The three compounds showed a sugar ring conformation rare among HIV-inhibitory nucleosides, probably due to the presence, at the 3'-position of the spiro moiety
Publisher version (URL)http://dx.doi.org/10.1080/07328319708006191
Appears in Collections:(CENQUIOR) Artículos
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