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Título: | A new and efficient one-pot synthesis of pyrido[2,1-f]purine-2,4-diones starting from 6-aminouracil derivatives |
Autor: | Peréz-Pérez, María-Jesús CSIC ORCID ; Priego, Eva María CSIC ORCID; Jimeno, M. Luisa CSIC ORCID; Camarasa Rius, María José CSIC ORCID | Palabras clave: | heterocycles tricyclic compounds pyridines halogenation N-bromosuccinimide |
Fecha de publicación: | 2002 | Editor: | Thieme | Citación: | Synlet 1 : 155-157 (2002) | Resumen: | A convenient synthesis of pyrido[2,1-f]purine-2,4-diones is described by reaction of 6-aminouracil derivatives with N-bromosuccinimide (NBS) followed by in situ reaction with pyridine or 4-substituted pyridines. A detailed study of the reaction conditions has been performed and a mechanism involving a 5,5-dibromo derivative is proposed. | Versión del editor: | http://dx.doi.org/10.1055/s-2002-19342 | URI: | http://hdl.handle.net/10261/35271 | DOI: | 10.1055/s-2002-19342 | ISSN: | 0936-5214 |
Aparece en las colecciones: | (CENQUIOR) Artículos |
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