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dc.contributor.authorSánchez-Moreno, Concepción-
dc.contributor.authorCano, M. Pilar-
dc.contributor.authorAncos, Begoña de-
dc.contributor.authorPlaza, Lucía-
dc.contributor.authorOlmedilla-Alonso, Begoña-
dc.contributor.authorGranado Lorencio, Fernando-
dc.contributor.authorMartín, Antonio-
dc.date.accessioned2011-04-13T11:46:33Z-
dc.date.available2011-04-13T11:46:33Z-
dc.date.issued2003-09-
dc.identifier.citationAmerican Journal of Clinical Nutrition 78(3): 454-460 (2003)es_ES
dc.identifier.issn0002-9165-
dc.identifier.urihttp://hdl.handle.net/10261/34607-
dc.description7 páginas, 1 figura, 4 tablas.-- Comunicación presentada al Phytochemical Society of Europe (PSE) Symposium on Dietary Phytochemicals and Human Health, celebrado en Salamanca (España) en Abril de 2002.es_ES
dc.description.abstract[Background]: Consumption of fruit and vegetables is associated with improved health and a decreased prevalence of chronic degenerative processes. [Objectives]: The objectives were to assess the bioavailability of vitamin C from orange juice and its influence on plasma vitamin C and 8-epi-prostaglandin F2α (8-epi-PGF2α) concentrations in a healthy human population. [Design]: Six men and 6 women consumed 500 mL commercial fresh-squeezed orange juice/d for 14 d, corresponding to an intake of 250 mg ascorbic acid/d. On the first day of the study, the subjects drank the juice in one dose (dose-response study), and on days 2–14 they consumed 250 mL in the morning and 250 mL in the afternoon. Blood was collected every hour for 6 h on the first day and again on days 7 and 14. [Results]: Baseline plasma vitamin C concentrations were significantly higher (P = 0.03) among the women than among the men (56.4 ± 4.4 compared with 44.3 ± 3.5 µmol/L). In the dose-response study, the maximum increase in plasma vitamin C occurred 3 h postdose in both the men and the women. Vitamin C concentrations remained significantly higher on days 7 and 14 than at baseline. Baseline concentrations of 8-epi-PGF2α were significantly higher (P = 0.03) among the men than among the women (249.6 ± 25.4 compared with 177.7 ± 6.2 pg/mL) but decreased significantly (P = 0.04) by day 14 of the intervention. A significant inverse correlation was observed between vitamin C and 8-epi-PGF2α (r = -0.791, P = 0.0022). Among smokers, baseline vitamin C was lower and 8-epi-PGF2α higher than among nonsmokers. [Conclusions]: Drinking orange juice (500 mL/d) increases plasma concentrations of vitamin C and reduces concentrations of 8-epi-PGF2α in humans. These effects were significantly more pronounced in smokers.es_ES
dc.description.sponsorshipSupported in part by the Coordinated Project CAM 07G/0040/2000- CAM 07G/0041/2000, Comunidad Autónoma de Madrid, Madrid (to MPC), and a Fulbright/Ministry of Education, Culture and Sports Award for Postdoctoral Research in the United States of America, Visiting Scholar Program, Commission for Cultural, Educational and Scientific Exchange between the United States of America and Spain (to CSM).es_ES
dc.language.isoenges_ES
dc.publisherAmerican Society for Nutritiones_ES
dc.rightsclosedAccesses_ES
dc.subjectOrange juicees_ES
dc.subjectVitamin Ces_ES
dc.subjectBioavailabilityes_ES
dc.subjectF2-isoprostaneses_ES
dc.subjectUric acides_ES
dc.subjectFood-frequency questionnairees_ES
dc.subjectSmokinges_ES
dc.titleEffect of orange juice intake on vitamin C concentrations and biomarkers of antioxidant status in humanses_ES
dc.typeartículoes_ES
dc.description.peerreviewedPeer reviewedes_ES
dc.relation.publisherversionhttp://www.ajcn.org/content/78/3/454.fulles_ES
dc.type.coarhttp://purl.org/coar/resource_type/c_6501es_ES
item.openairetypeartículo-
item.cerifentitytypePublications-
item.languageiso639-1en-
item.grantfulltextnone-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextNo Fulltext-
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