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Tissue-type plasminogen activator (T-PA) inhibitors with a therapeutic capacitu.

Other TitlesInhibidores del activador tisular del plasmingeno (T-PA) con capacidad terapeutica.
AuthorsPaciucci, Rosana; Díaz, Víctor; Thomson, Timothy M.
Issue Date21-Aug-2003
CitationWO 03/068950 A1
Abstract[EN]The invention relates to the tissue-type plasminogen activator (t-PA) which is a serine protease that is overexpressed in various different types of tumours, including cancer of the pancreas, melanomas and neuroblastomas. More specifically, the invention relates to t-PA activity and expression inhibitors that have been developed as antitumour agents. [ES]El activador tisular del plasminógeno (t-PA) es una serina proteasa sobreexpresada en varios tipos de tumores, incluyendo cáncer de páncreas, melanomas y neuroblastomas. En la presente invención han sido desarrollados inhibidores de la expresión y actividad del t-PA como agentes antitumorales.
DescriptionFecha de solicitud: Titulares: Consejo Superior de Investigaciones Científicas (CSIC).- Hospital Vall d´Hebron .- Reventos Puigjaner.
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