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http://hdl.handle.net/10261/29971
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Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Enjuanes Sánchez, Luis | - |
dc.date.accessioned | 2010-12-14T10:06:00Z | - |
dc.date.available | 2010-12-14T10:06:00Z | - |
dc.date.issued | 2001-06-07 | - |
dc.identifier.citation | WO 01/39797 A2 | es_ES |
dc.identifier.uri | http://hdl.handle.net/10261/29971 | - |
dc.description | Fecha de solicitud:30.11.2000.- Titular: Consejo Superior de Investigaciones Científicas (CSIC). | es_ES |
dc.description.abstract | The present invention relates to methods of preparing a DNA comprising steps, wherein (a) a DNA comprising a full length copy of the genomic RNA (gRNA) or an RNA virus; or (b) a DNA comprising one or several fragments of a gRNA of an RNA virus, which fragments code for an RNA dependent RNA polymerase and at least one structural or non-structural protein; or (c) a DNA having a homology of at least 60% to the sequences of (a) or (b); is cloned into a bacterial artificial chromosome (BAC).; Additionally, DNAs are provided, which comprise sequences derived from the genomic RNA (gRNA) of a coronavirus which sequences have a homology of at least 60% to the natural sequence of the virus and code for an RNA dependent RNA polymerase and at least one structural or no-structural protein, wherein a fragment of said DNA is capable of being transcribed into RNA which RNA can be assembled to a virion. Further, the use of these nucleic acids for preparation of viral RNA or virions as well as pharmaceutical preparations comprising these DNAs, viral RNAs or virions is disclosed. | es_ES |
dc.language.iso | eng | es_ES |
dc.rights | openAccess | es_ES |
dc.title | Infectious clones | es_ES |
dc.type | patente | es_ES |
dc.description.peerreviewed | Peer reviewed | es_ES |
dc.type.coar | http://purl.org/coar/resource_type/c_15cd | es_ES |
item.openairetype | patente | - |
item.grantfulltext | open | - |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | With Fulltext | - |
item.languageiso639-1 | en | - |
Aparece en las colecciones: | (CNB) Patentes |
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WO0139797A2.pdf | 4,16 MB | Adobe PDF | Visualizar/Abrir |
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