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| Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.contributor.author | Soriano, Francisco | - |
| dc.contributor.author | Rodríguez-Cerrato, Violeta | - |
| dc.contributor.author | García, Pedro | - |
| dc.contributor.author | Huelves, Lorena | - |
| dc.contributor.author | García, Ernesto | - |
| dc.contributor.author | Prado, Gema del | - |
| dc.contributor.author | Gracia, Matilde | - |
| dc.contributor.author | Ponte, Carmen | - |
| dc.contributor.author | López, Rubens | - |
| dc.date.accessioned | 2008-02-06T12:32:45Z | - |
| dc.date.available | 2008-02-06T12:32:45Z | - |
| dc.date.issued | 2007-06-18 | - |
| dc.identifier.citation | Antimicrob Agents Chemother. 2007 September; 51(9): 3371–3373 | en_US |
| dc.identifier.citation | PMCID: 2043201 | en_US |
| dc.identifier.issn | 0066-4804 | - |
| dc.identifier.uri | http://hdl.handle.net/10261/2875 | - |
| dc.description.abstract | The in vitro and in vivo antipneumococcal activities of the main pneumococcal autolysin (LytA) and Cpl-1, a lysozyme encoded by phage Cp-1, were studied. Intraperitoneal therapy with LytA or high-dose Cpl-1 remarkably reduced peritoneal bacterial counts (>5 log10 CFU/ml) compared with those for the controls. After intravenous injection, LytA was the most effective treatment. | en_US |
| dc.description.sponsorship | This research was supported by grants from the Red Tematica de Investigacion Cooperativa Spanish Pneumococcal Infection Study Network (grant G03/103) (Ministerio de Sanidad y Consumo, Spain) and the program COMBACT Nuevas Dianas para Combatir a las Bacterias Patogenas (grant S-BIO-026-2006) (Consejerıa de Educacion, Comunidad de Madrid, Madrid, Spain). L.H. and G.D.P. received scholarships from the Fundacio´n Conchita Ra´bago; M.G. received a scholarship from the Fondo de Investigaciones Sanitarias, Ministerio de Sanidad y Consumo, Spain. | en_US |
| dc.format.extent | 71359 bytes | - |
| dc.format.mimetype | application/pdf | - |
| dc.language.iso | eng | en_US |
| dc.publisher | American Society for Microbiology | en_US |
| dc.rights | closedAccess | en_US |
| dc.title | Pneumococcal LytA Autolysin, a Potent Therapeutic Agent in Experimental Peritonitis-Sepsis Caused by Highly β-Lactam-Resistant Streptococcus pneumoniae | en_US |
| dc.type | artículo | en_US |
| dc.identifier.doi | 10.1128/AAC.00137-07 | - |
| dc.description.peerreviewed | Peer reviewed | en_US |
| dc.identifier.pmid | 17576844 | - |
| dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
| item.openairetype | artículo | - |
| item.grantfulltext | none | - |
| item.cerifentitytype | Publications | - |
| item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
| item.fulltext | No Fulltext | - |
| item.languageiso639-1 | en | - |
| Aparece en las colecciones: | (CIB) Artículos | |
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