Please use this identifier to cite or link to this item:
http://hdl.handle.net/10261/2872
Share/Export:
![]() |
|
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Title: | Polyclonal B-cell activation by a synthetic analogue of bacterial lipoprotein is functionally different from activation by bacterial lipopolysaccharide |
Authors: | Martínez-Alonso, Carlos; Kleine, B.; Sprenger, R.; Bessler, W. G | Issue Date: | May-1987 | Publisher: | British Society for Immunology | Citation: | Immunology 1987 May; 61(1): 29–34. | Abstract: | The reactivity of 38 murine strains to a synthetic analogue of bacterial lipoprotein, tripalmitoyl-pentapeptide (TPP), was tested and compared with the reactivity to lipopolysaccharide (LPS). These strains include common laboratory mice and H-2 recombinant inbred lines, as well as some newly bred lines originating from animals recently captured in different regions of Europe. All animals analysed were reactive to TPP and polyclonally activated to proliferation and immunoglobulin synthesis. Large differences in mitogen reactivities of various H-2 recombinant inbred strains suggest that MHC or closely linked gene products influence the reactivity to the LPS and TPP mitogens. By analysing the frequencies of precursor cells reactive to TPP or LPS and the isotype patterns obtained after stimulation, we demonstrated that both mitogens activate individual B cells in different ways. | URI: | http://hdl.handle.net/10261/2872 |
Appears in Collections: | (CNB) Artículos |
Show full item record
Review this work
PubMed Central
Citations
2
checked on May 20, 2022
SCOPUSTM
Citations
10
checked on May 20, 2022
WEB OF SCIENCETM
Citations
12
checked on May 19, 2022
Page view(s)
255
checked on May 21, 2022
Google ScholarTM
Check
Dimensions
WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.