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Murine stem cells and applications thereof

AuthorsSánchez García, Isidro ; Pérez-Caro, M.; Voces, Felipe
Issue Date28-Dec-2006
CitationInternational Publication Number: WO 2006/136951 A3
AbstractThe invention relates to animal solid tumour models which comprise a transgenic non-human mammal containing in its genome a DNA construct that comprises a gene created and/or activated by a genetic anomaly associated with human cancer operatively bound to a promoter that directs the expression of the gene in Scal+ cells. The invention also relates to stem cells capable of specifically expressing in stem cells human genetic anomalies associated with human pathologies. Applications of these models and stem cells, such as diagnostic, therapeutic and prophylactic applications for human diseases, and products and methods are provided.
DescriptionFiling Date: 2006-05-24.--Priority Data: EP 05076219.4 (2005-05-24)
Appears in Collections:(IBMCC) Patentes
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