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Título: | Keggin-type polyoxometalates as Cu(ii) chelators in the context of Alzheimer's disease |
Autor: | Atrián-Blasco, Elena CSIC ORCID CVN ; Cremoux, Lucie de; Li, Xudong; Mitchell-Heggs, Rufus; Sabater, Laurent; Blanchard, Sébastien; Hureau, Christelle | Fecha de publicación: | 2022 | Editor: | Royal Society of Chemistry (UK) | Citación: | Chemical Communications 58(14): 2367-2370 (2022) | Resumen: | Two Keggin polyoxometalates were used as new copper ligands to counteract the effects of CuII(Amyloid-β) interaction. Their ability to remove CuII from CuII(Amyloid-β), to stop CuII(Amyloid-β) induced formation of reactive oxygen species and to restore apo-like self-assembly of CuII(Amyloid-β) was shown. | Versión del editor: | https://doi.org/10.1039/d1cc05792h | URI: | http://hdl.handle.net/10261/280384 | DOI: | 10.1039/d1cc05792h | ISSN: | 1364-548X |
Aparece en las colecciones: | (INMA) Artículos |
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