Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/278957
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Título: | Synthesis of Tetrahydroazepines through Silyl Aza-Prins Cyclization Mediated by Iron(III) Salts |
Autor: | Sinka, Victoria CSIC ORCID; Fernández, Israel; Padrón, Juan I. CSIC ORCID | Palabras clave: | Aldehydes amines catalysts cyclization lipids |
Fecha de publicación: | 17-ago-2022 | Editor: | ACS Publications | Citación: | Journal of Organic Chemistry, 87(17), 11735–11742 (2022) | Resumen: | A new methodology for the synthesis of seven-membered unsaturated azacycles (tetrahydroazepines) was developed. It is based on the powerful aza-Prins cyclization in combination with the Peterson-type elimination reaction. In a single reaction step, a C–N, C–C bond and an endocyclic double bond are formed. Under mild reaction conditions and using iron(III) salts as sustainable catalysts, tetrahydroazepines with different degrees of substitution are obtained directly and efficiently. DFT calculations supported the proposed mechanism. | Versión del editor: | https://doi.org/10.1021/acs.joc.2c01396 | URI: | http://hdl.handle.net/10261/278957 | DOI: | 10.1021/acs.joc.2c01396 | ISSN: | 0022-3263 | E-ISSN: | 1520-6904 |
Aparece en las colecciones: | (IPNA) Artículos |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
Synthesis-Sinka_et_al-2022-JOC.pdf | Artículo principal | 1,96 MB | Adobe PDF | Visualizar/Abrir |
CORE Recommender
SCOPUSTM
Citations
3
checked on 24-abr-2024
WEB OF SCIENCETM
Citations
2
checked on 19-feb-2024
Page view(s)
73
checked on 22-abr-2024
Download(s)
39
checked on 22-abr-2024
Google ScholarTM
Check
Altmetric
Altmetric
Este item está licenciado bajo una Licencia Creative Commons