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Title

Data from: Neandertal and Denisovan DNA from Pleistocene sediments

AuthorsSlon, Viviane; Hopfe, Charlotte; Weiß, Clemens L.; Mafessoni, Fabrizio; De la Rasilla, Marco; Lalueza-Fox, Carles CSIC ORCID
AGROVOC ThesaurusPleistoceno
ADN
Sedimento
Issue Date13-Mar-2018
PublisherDryad
CitationSlon, Viviane; Hopfe, Charlotte; Weiß, Clemens L.; Mafessoni, Fabrizio; De la Rasilla, Marco; Lalueza-Fox, Carles. (2018). Data from: Neandertal and Denisovan DNA from Pleistocene sediments [Dataset]; Dryad; Version 1; https://doi.org/10.5061/dryad.m2dk7
AbstractAlthough a rich record of Pleistocene human-associated archaeological assemblages exists, the scarcity of hominin fossils often impedes the understanding of which hominins occupied a site. Using targeted enrichment of mitochondrial DNA we show that cave sediments represent a rich source of ancient mammalian DNA that often includes traces of hominin DNA, even at sites and in layers where no hominin remains have been discovered. By automation-assisted screening of numerous sediment samples we detect Neandertal DNA in eight archaeological layers from four caves in Eurasia. In Denisova Cave we retrieved Denisovan DNA in a Middle Pleistocene layer near the bottom of the stratigraphy. Our work opens the possibility to detect the presence of hominin groups at sites and in areas where no skeletal remains are found.
DescriptionMultiple sequence alignment files This submission contains multiple sequence alignment files used for phylogenetic reconstructions. Sequences reconstructed from sediments are denominated by the site and layer of origin. The comparative data (identical in all files) is identified by the name of the individual and the accession code of its mtDNA sequence. MSA_sedimentDNA.zip
Publisher version (URL)https://doi.org/10.5061/dryad.m2dk7
URIhttp://hdl.handle.net/10261/278288
DOI10.5061/dryad.m2dk7
ReferencesSlon, Viviane; Hopfe, Charlotte; Weiß, Clemens L.; Mafessoni, Fabrizio; De la Rasilla, Marco; Lalueza-Fox, Carles; Rosas, Antonio ; Soressi, M.; Knul, M.V.; Miller, R.; Stewart, J.R.; Derevianko, Anatoly P.; Jacobs, Z.; Li, B.; Roberts, R.G.; Shunkov, Michael V.; De Lumley, H.; Perrenoud, C.; Guši¿, I.; Ku¿an, Ž.; Rudan, P.; Aximu-Petri, A.; Essel, Elena; Nagel, S.; Nickel, B.; Schmidt, A.; Prüfer, K.; Kelso, J.; Burbano, H.A.; Pääbo, S.; Meyer, M. Neandertal and Denisovan DNA from Pleistocene sediments. https://doi.org/10.1126/science.aam9695. http://hdl.handle.net/10261/159780
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