Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/27204
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dc.contributor.authorGaspar, Helena-
dc.contributor.authorMoiteiro, Cristina-
dc.contributor.authorSardinha, Joao-
dc.contributor.authorGonzález-Coloma, Azucena-
dc.date.accessioned2010-08-20T07:26:54Z-
dc.date.available2010-08-20T07:26:54Z-
dc.date.issued2008-
dc.identifier.citationNatural Product Communications 3(9):1457-1464 (2008)en_US
dc.identifier.issn1934-578X-
dc.identifier.urihttp://hdl.handle.net/10261/27204-
dc.description8 pages, figures, and tables statistics.en_US
dc.description.abstractNew semisynthetic sesquiterpene derivatives (3-7, 10), together with two known ones (8-9) were prepared from (S)-(+)- curcuphenol (1), isolated from the Caribbean sponge Didiscus oxeata. The natural sesquiterpenes 1 and (S)-(+)-curcudiol (2), as well as semisynthetic derivatives 3-10, were evaluated against the herbivorous insect species Spodoptera littoralis, Leptinotarsa decemlineata and Rhopalosiphum padi. All compounds had an antifeedant effect on L. decemlineata. With R. padi, a structure-dependent antifeedant response was observed, with 1 being the most active, followed by 4 and 5. Furthermore, compounds 1, 4, 5, 7, 8 and 10 reduced S. littoralis larval weight, with 10 also reducing ingestion by S. littoralis larvae. Of the derivatives studied here, none showed stronger effects (either antifeedant or postingestive) than the parent compound 1. It can, therefore, be concluded that the structure of the side chain and the presence of the phenol ring of curcuphenol are important structural requirements for its insect antifeedant and growth regulation effects.en_US
dc.format.extent22195 bytes-
dc.format.mimetypeapplication/pdf-
dc.language.isoengen_US
dc.publisherNatural Product Communicationsen_US
dc.rightsclosedAccessen_US
dc.subjectDidiscus oxeataen_US
dc.subjectSesquiterpenoidsen_US
dc.subject(s)-(+)-curcuphenol derivativesen_US
dc.subjectSpodoptera littoralisen_US
dc.subjectLeptinotarsa decemlineataen_US
dc.subjectRhopalosiphum padien_US
dc.subjectAntifeedantsen_US
dc.titleBioactive Semisynthetic Dervatives of (S)-(+)-Curcuphenolen_US
dc.typeartículoen_US
dc.description.peerreviewedPeer revieweden_US
item.languageiso639-1en-
item.cerifentitytypePublications-
item.grantfulltextnone-
item.openairetypeartículo-
item.fulltextNo Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
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