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Sequential biocatalytic resolution of trans-cyclohexane-1,2-diamine. Chemoenzymatic Synthesis of an optically active polyamine

AuthorsTorres, Oliver; Alfonso, Ignacio ; Gotor, Vicente
Issue Date7-Aug-2004
PublisherRoyal Society of Chemistry (UK)
CitationChemical Communications 15: 1724 - 1725 (2004)
AbstractA new enzymatic process is described. Different preparations of lipase B from Candida antarctica are able to catalyse Michael-type addition of secondary amines to acrylonitrile. This new reaction widens the applicability of these biocatalysts in organic synthesis.
Description2 pages, 1 figure, 2 schemes, 1 table.-- PMID: 15278156 [PubMed].-- Available online Jun 28, 2004.
Publisher version (URL)http://dx.doi.org/10.1039/b402244k
Appears in Collections:(IQAC) Artículos
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